Sous Vide Pork Tenderloin with Chili Rub

With a dynamite spice rub this pork tenderloin has a supple texture with bold Southwest flavors
Sous Vide Pork Tenderloin Recipe

By Mark Hinds | Updated January 23, 2026

One of the easiest ways to get a pork tenderloin to turn out perfectly is to cook itย sous vide. To createย a sousย vide pork tenderloin that standouts from the crowd, this recipe uses a combination of chili powder and a hint of chipotle to create one with the bold flavors of the Southwest.

The best reason for cooking a pork tenderloin sous vide is how easy it is to get the pork just right, with a little pink in the center and a nice crisp crust on the outside.

What makes this recipe so delicious is how the chili powder rub on the outside helps create a crisp crust and flavors that pop!

Making Pork Tenderloin Taste Delicious

Pork tenderloin is a lean, tender cut that is ideal for cooking sous vide. What makes tenderloin such a good cut is its soft supple texture and ability to absorb flavors from spices and marinades. The flip side of its ability to absorb flavors is that when a tenderloin is under-seasoned all it has to offer is texture.

Pork In Bag
Little tenderloins all ready for their bath

There are so many sous vide recipes that use herbs and other aromatics for pork tenderloin that we wanted to do something special with ours and create a unique recipe with bold flavors that took advantage of the porkโ€™s tenderness to create a memorable dish.

Since pork tenderloin is as close as you can get to a blank canvas when youโ€™re cooking, we decided to use the deep, smoky flavors of the Southwest. We love how the combination of ancho chili, cumin, and other spices add layers of flavor โ€“ especially when they become the base for the crust that forms when the tenderloin is finished.

In addition to using a good chili powder, our spice rub adds a little chipotle for heat and garlic powder to round out the flavors. We also give the tenderloin a rubdown with some lemon juice to help the spices adhere to the pork and to brighten the dishโ€™s flavors.

One of the best ways weโ€™ve found to elevate pork dishes is to add a little lemon or lime juice or apple cider vinegar to the pork before its cooked. Adding any of the three gives the pork a slight twang.

Tips for Better Sous Vide

There are a lot of things that people do when theyโ€™re roasting or grilling pork tenderloin that does not need to be done when itโ€™s cooked sous vide. One of the most significant advantages of cooking sous vide is that it locks in an ingredientโ€™s moisture, meaning thereโ€™s no reason to brine something before cooking.

Also, since the pork is cooked at a consistent temperature, thereโ€™s no need to let it rest when it comes out of the water bath.

For appearance and taste, it does need to be finished. The two easiest ways to finish one is to sear it in a hot pan with a little oil for a few minutes or on the grill.

In either case, pat the tenderloin dry before putting it on the heat, and make sure to turn it every few minutes until it develops a nice crust on each side.

Tenderloin Being seared
Searing the tenderloin helps to bring out the spice rubs flavors

In our testing, we found that thereโ€™s no advantage to searing the tenderloin before cooking it sous vide, it essentially came out the same as the ones we didnโ€™t pre-sear.

We like the tenderloin cooked at 133โ„‰ (56ยบC), which produces a nice pink middle with a soft texture. If you want your pork a little more done just increase the temperature a few degrees.

The general temperature range for pork tenderloin cooked sous vide is between 130ยบF (54ยบC) and 140ยบF (60ยบC) for medium-rare and between 140ยบF and 150ยบF (65ยบC) for medium. Pork tenderloin cooked sous vide can be cooked beyond a medium 150ยบF (65ยบC), but itโ€™s not our thing.

Thereโ€™s a lot of flexibility when it comes to sous vide pork tenderloin cooking times. Our recommendation is to cook it for 1 to 3 hours to let the flavors from the spice rub soak in and the pork develop the right level of tenderness.

If youโ€™re interested in learning more about sous vide read What is Sous Vide Cooking and Why it Works.

Sous Vide Pork Tenderloin Recipe
The flavors in the pork are amazing with our Ancho chili sweet potato puree.

We usually serve this pork tenderloin as the main dish in a nice meal. It also makes some of the best tacos youโ€™ve ever had when itโ€™s cut up into bite-sized pieces and served with a little mango salsa and shredded pepper jack cheese.

Try pairing the tenderloin with our Ancho Chili Sweet Potato Puree or Sweet Corn with Anaheim Peppers.

Sous Vide Pork Tenderloin Recipe

Sous Vide Pork Tenderloin with Chili Rub

4.5 from 27 votes
One of the easiest ways to get a pork tenderloin to turn out perfectly is to cook it sous vide. To create a sous vide pork tenderloin that standouts from the crowd this recipe uses a combination of chili powder and a hint of chipotle to create one with the bold flavors of the Southwest.
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Prep Time: 15 minutes
Cook Time: 3 hours
Total Time: 3 hours 15 minutes
Servings: 3 servings

Ingredients

  • 1 lb pork tenderloin
  • 2 tsp lemon juice
  • 1 tsp chili powder
  • 1/2 tsp garlic powder
  • 1/4 tsp chipotle
  • 1 tsp salt
  • 1/2 tsp pepper

Instructionsย 

  • In a small bowl combine the chili, chipotle, and garlic powders with the salt and pepper
  • Trim any loose pieces or extra fat from the pork and rub it down with the lemon juice.
  • Coat the tenderloin with the spices, seal it inside a bag, and place it into a water bath at 133ยบF for at least 1 hour and up to 3 hours.
  • When the tenderloin has finished cooking, remove it from the bath, and pat it dry with a paper towel.
  • To finish on the stove sear it in a hot pan with a little olive oil for 2 to 3 minutes a side.
    If youโ€™re finishing it on the grill, preheat the grill to medium-high and grill the tenderloin for 2 to 3 minutes per side.
    The goal for either method is to use medium-high heat to develop a nice crust on the outside without over cooking the middle.
  • To serve slice the pork into rounds around an inch thick.

Notes

If youโ€™re just getting started cooking sous vide check out our story on Getting Started Cooking Sous Vide. Umami also has a whole section on Sous Vide that has all the stories, recipes, and equipment you need.
Tried this RecipeLet us know what you think of this recipe. Leave us your thoughts and rating.
Nutrition
Calories: 187kcal | Carbohydrates: 1g | Protein: 31g | Fat: 5g | Saturated Fat: 1g | Cholesterol: 98mg | Sodium: 875mg | Potassium: 611mg | Vitamin A: 265IU | Vitamin C: 1.3mg | Calcium: 9mg | Iron: 1.6mg

The nutrition information shown is an estimate based on available ingredients and preparation.

Mark is an experienced food writer, recipe developer, and photographer who is also Umamiโ€™s publisher and CEO. A passionate cook who loves to cook for friends, he can often be found in the kitchen or by the grill testing new recipes.

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4.52 from 27 votes (26 ratings without comment)

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Responses

  1. David B

    5 stars
    Excellent! I was anxious to try this but didn’t have the two chilies, but did have some guajilloes so substituted that. Will definitely make again after I get to the store for the anchos and cascabels. Thanks for a great recipe.

    1. Glad you like it and thanks for leaving us a note!